FUNCTIONAL MITRAL REGURGITATION
Clinical trials for FUNCTIONAL MITRAL REGURGITATION explained in plain language.
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Heart failure drug combo shows promise for leaky valve patients
Disease control CompletedThis study tested whether adding sacubitril-valsartan to standard care helps people with heart failure (with preserved pumping ability) and a leaky mitral valve. 84 participants were randomly assigned to get the drug or standard care alone. Researchers measured heart function and…
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Phase: PHASE4 • Sponsor: Ziekenhuis Oost-Limburg • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Heart failure drug combo may improve valve function
Disease control CompletedThis completed study in 180 heart failure patients compared the effects of taking Entresto alone versus Entresto plus a second drug (empagliflozin) on mitral valve function and heart pumping ability. Participants had heart failure with reduced ejection fraction and some degree of…
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Phase: NA • Sponsor: Rehab Werida • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New catheter procedure tightens leaky heart valves without surgery
Disease control CompletedThis early study tested a new, less invasive procedure to treat functional mitral regurgitation, a condition where a leaky heart valve causes heart failure symptoms like shortness of breath and fatigue. Nineteen adults with this condition received a permanently implanted device t…
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Phase: NA • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC