FUNCTIONAL MITRAL REGURGITATION
Clinical trials for FUNCTIONAL MITRAL REGURGITATION explained in plain language.
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New heart valve device shows promise for severe leaky valve patients
Disease control OngoingThis study tested a new device called the Tendyne Transcatheter Mitral Valve System to treat people with a severe leaky heart valve (mitral regurgitation). About 103 participants received either the Tendyne device or another approved device. The goal was to see if the new valve i…
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 17, 2026 11:20 UTC
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New combo drug may ease strain on failing hearts with leaky valves
Disease control OngoingThis study looks at whether adding sacubitril-valsartan to standard care helps people with heart failure (where the heart pumps normally but is stiff) and a moderate or worse leaky mitral valve. About 84 adults will take either the study drug plus usual treatment or usual treatme…
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Phase: PHASE4 • Sponsor: Ziekenhuis Oost-Limburg • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New heart valve clip shows promise in major trial
Disease control OngoingThis study tests a new device called PASCAL against an existing one, MitraClip, to fix leaky mitral valves without open-heart surgery. About 1,200 people with severe mitral regurgitation who are too high-risk for surgery took part. The goal is to see if PASCAL is as safe and effe…
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 12, 2026 13:39 UTC