FUNCTIONAL MITRAL REGURGITATION
Clinical trials for FUNCTIONAL MITRAL REGURGITATION explained in plain language.
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Can a tiny implant fix a leaky heart valve without open surgery?
Disease control TerminatedThis trial is testing a new device called the PLAR Implant, which is designed to treat severe functional mitral regurgitation—a condition where the heart's mitral valve doesn't close properly, causing blood to leak backward. The implant is placed via a catheter through a vein in …
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Phase: NA • Sponsor: Polares Medical SA • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New heart valve implant offers hope for patients too sick for surgery
Disease control OngoingThis study tests a new device called Tendyne, which is a replacement heart valve placed through a tube in the blood vessels, avoiding open-heart surgery. It is for people with a leaky mitral valve (mitral regurgitation) who are too high-risk for traditional surgery. The trial com…
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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New heart valve fix device takes on market leader in major trial
Disease control OngoingThis study compares two devices—the Edwards PASCAL and the Abbott MitraClip—that repair leaky mitral heart valves without open-heart surgery. About 1,200 people with severe mitral regurgitation who are too high-risk for surgery are being randomly assigned to one device. The goal …
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Heart rhythm fix may also repair leaky valve: scientists build prediction model
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at people with persistent atrial fibrillation (an irregular heartbeat) and moderate-to-severe functional mitral regurgitation (a leaky heart valve). Researchers want to see if a procedure called catheter ablation—which zaps abnormal heart tissue to restore normal…
Matched conditions: FUNCTIONAL MITRAL REGURGITATION
Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC