FRONTOTEMPORAL DEMENTIA

This study tested an experimental drug called AL001 in 33 people who carry specific gene mutations that cause frontotemporal dementia (FTD), a brain disease that affects personality and language. The main goal was to check if the drug is safe and how the body processes it. Resear…

This study tested an experimental drug called TPN-101 in 42 people with ALS or frontotemporal dementia caused by a specific gene change (C9orf72). The main goal was to see if the drug is safe and tolerable over 48 weeks. Researchers also looked at how the drug moves in the body a…

This study tested an online tool called WeCareAdvisor designed to help caregivers of people with dementia manage difficult behaviors like agitation or aggression. 262 caregivers used the tool to track symptoms, get personalized tips, and reduce their own stress. The goal was to s…

This study tested a dementia care program delivered by phone and internet, where trained navigators supported patients and caregivers. Over 1,200 people with various types of dementia and their caregivers took part across six health systems. The goal was to see if this approach i…

This study tested a video-based support program for 16 family caregivers of people with frontotemporal dementia (FTD). The program aimed to reduce caregiver stress and improve quality of life by providing education and emotional support through videoconference sessions. Results m…

This pilot study tested whether wearable sensors can measure apathy in real-life situations for people with frontotemporal dementia and healthy volunteers. 14 participants wore sensors that tracked movement, body position, and energy use. The goal was to see if this technology ca…

This study looked at how people with Alzheimer's disease or a type of frontotemporal dementia recall personal memories. Researchers analyzed whether memories were specific events or more general. 39 participants took part to help understand memory changes in these conditions.

This study examined over 2,200 people with frontotemporal dementia (FTD) or symptoms of it to find out how many cases are linked to specific genes. Researchers collected genetic samples to better understand the causes of this rare brain disease. The goal was to gather knowledge, …

This study looked at how the prefrontal cortex helps us think in analogies and categories. Researchers tested healthy volunteers and patients with frontotemporal dementia or progressive supranuclear palsy using tasks that measure reaction time and accuracy. They also used brain s…

This study interviewed 26 adults who either have behavioral variant frontotemporal dementia (bvFTD) or carry a gene that puts them at risk. The goal was to learn how the condition affects daily life, emotions, and coping. No treatments or medications were tested.

This study examined 186 people with Alzheimer's, Lewy body, frontotemporal, or corticobasal dementia, plus healthy controls, to see if subtle physical signs (like coordination or reflexes) differ between dementia types. Participants had simple exams and cognitive tests. The goal …