FRONTOTEMPORAL DEGENERATION

This study tests whether the drug vortioxetine can improve mood symptoms and thinking skills in people with early-stage behavioral variant frontotemporal dementia (bvFTD). About 50 participants will take vortioxetine for 12 weeks and undergo brain scans and cognitive tests before…

This study is building a large collection of health information and biological samples from 150 people with ALS and related disorders. Researchers will track changes in muscle function, breathing, speech, and quality of life over time. The goal is to provide this data to scientis…

This study follows nearly 3,000 people, including healthy adults and those with memory or movement problems, to learn how brain diseases like Alzheimer's and Parkinson's develop. Researchers use advanced brain scans and tests to track changes over time. The goal is to improve ear…

This study is testing whether simple blood tests and brain scans can help family doctors diagnose Alzheimer's disease and other dementias earlier and more accurately. Researchers will recruit 1,200 people with mild memory or thinking problems from primary care clinics. The goal i…

This study is testing whether new blood tests can accurately diagnose the cause of memory problems, potentially replacing the need for more invasive spinal fluid tests. Researchers will compare blood test results with spinal fluid results in 1,200 people being evaluated at a memo…