FOOD ALLERGY

This study tested whether adding the drugs omalizumab (Xolair) or dupilumab (Dupixent) to oral immunotherapy (OIT) helps people with multiple food allergies tolerate more allergens. 130 participants aged 4 to 55 with allergies to peanut plus one or two other foods were enrolled. …

This study tested a home-based, dietitian-led 'egg ladder' for infants newly diagnosed with egg allergy. Over 12 months, babies gradually ate more cooked egg, starting with baked goods. The goal was to see if this approach is safe and feasible. 109 infants participated, and resea…

This phase 2 study tested whether the drug omalizumab (Xolair) can make oral immunotherapy safer for people with multiple food allergies. Sixty participants aged 2 to 25 received omalizumab before gradually increasing doses of their problem foods. The goal was to see if this appr…

This study looked at whether a blood test called the basophil activation test (BAT) can accurately diagnose food allergies in children, potentially replacing the need for oral food challenges (OFCs). Researchers tested 116 children aged 0-18 who were already scheduled for an OFC.…

This study looked at 107 people with severe food or insect allergies to measure the distance from skin to muscle in their thighs. The goal was to see if the needles on common epinephrine auto-injectors (like EpiPen) are long enough to deliver the medicine into the muscle, as reco…

This study tested a new drug called l-dipivefrin (IN-001) given under the tongue as a spray or drops, compared to standard epinephrine injections, in 32 healthy adults. The goal was to see how the body absorbs the drug and its safety. It is an early-stage study to gather informat…