FOLLICULAR LYMPHOMA

This study tested whether adding the drug ibrutinib to standard rituximab treatment works better than rituximab alone for people newly diagnosed with follicular lymphoma. Researchers enrolled 445 older adults or those with other health conditions to compare how long patients stay…

This study tested a one-time treatment called tisagenlecleucel, a type of CAR-T cell therapy, in adults whose follicular lymphoma had returned or stopped responding to other treatments. Doctors collected and reprogrammed each patient's own immune cells to better find and attack t…

This study tested a new type of personalized cell therapy for children and young adults whose leukemia or lymphoma had come back or did not respond to standard treatments. Researchers collected a patient's own immune cells, genetically modified them in a lab to recognize a protei…

This early-phase study tested the safety and best dose of a new drug called BGB-10188. It was given alone or combined with other cancer drugs to 97 patients with advanced blood cancers or solid tumors that had returned or stopped responding to prior treatments. The main goal was …

This study tested whether a treatment called axicabtagene ciloleucel, a type of CAR-T cell therapy, could help people with slow-growing non-Hodgkin lymphoma that had come back or stopped responding to other treatments. It involved 159 participants whose cancer had progressed afte…

This small study tested a new, more convenient way to give radiation therapy to people with hard-to-treat B-cell lymphoma before they received CAR T-cell therapy. Instead of daily treatments, participants received radiation once a week for five weeks. Researchers wanted to see if…

This large, completed Phase 3 trial tested if a combination of the drugs lenalidomide and rituximab could better control follicular lymphoma—a slow-growing but hard-to-cure blood cancer—compared to the standard treatment of rituximab plus chemotherapy. It involved over 1,000 adul…

This first-in-human study tested a new oral drug called BR101801 in adults with advanced blood cancers that had returned or stopped responding to other treatments. The main goals were to find a safe dose and see how the body processes the drug. Researchers also looked for early s…

This study tested a two-step, lower-intensity stem cell transplant for patients with high-risk blood cancers like leukemia and lymphoma. The goal was to use milder chemotherapy and radiation before the transplant to reduce side effects while still allowing the donor's immune cell…

This study aims to gather information on how well a cancer treatment called CAR T-cell therapy works for people living with HIV who also have certain blood cancers. Researchers will collect standard medical data from about 30 patients who have already received this therapy. The g…