ESRD

This study looks at whether canagliflozin, a drug used for diabetes, can safely reduce protein in the urine (a sign of kidney damage) in people with advanced chronic kidney disease (CKD), including those on dialysis. About 35 adults with CKD stage 4 or 5 will take the drug for up…

This study tested a device called VasQ that wraps around a surgically created blood vessel connection (fistula) used for dialysis in people with kidney failure. The device is designed to improve blood flow and reduce complications. 144 patients received the device and were follow…

This study tested a special collagen implant coated with sirolimus (rapamycin) placed around a new dialysis fistula during surgery. The goal was to see if it helps the fistula become usable for dialysis sooner and stay working longer. About 269 people with advanced kidney disease…

This phase 3 trial tests a sirolimus-releasing collagen implant placed around a new dialysis fistula during surgery. The goal is to help the fistula mature faster so it can be used for dialysis. The study involves 136 people aged 65+ with kidney failure who are new to hemodialysi…

This study follows 211 people with IgA nephropathy who previously took a 6-9 month course of the steroid methylprednisolone in the TESTING trial. Researchers want to see if the steroid helped prevent end-stage kidney disease (needing dialysis or a transplant) over the long term. …

This study tests a program designed to increase living donor kidney transplants among Hispanic patients with end-stage renal disease. The program provides Spanish-language education and outreach by bicultural health workers. Researchers will compare transplant rates between Hispa…

This pilot study tested a shared decision-making tool called the Donor Offer Plan (DOP) for people on the kidney transplant waiting list. 100 participants reviewed an online education module and discussed their donor preferences with a transplant nurse. The goal was to see if thi…