DYSTONIA
Clinical trials for DYSTONIA explained in plain language.
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Brain pacemaker offers hope for musicians with hand cramps
Disease control OngoingThis study tests if deep brain stimulation (DBS) can help people with severe focal hand dystonia, a condition causing uncontrollable muscle contractions in the hand. Five adults who haven't improved with botulinum toxin will undergo surgery to implant a device that sends electric…
Matched conditions: DYSTONIA
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Scientists track rare movement disorder to uncover genetic clues
Knowledge-focused OngoingThis study looks at people with rapid-onset dystonia-parkinsonism (RDP), a rare movement disorder. Researchers aim to find genetic mutations linked to the disease and document how symptoms develop and change over time. About 200 participants are involved, and the focus is on obse…
Matched conditions: DYSTONIA
Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated May 17, 2026 10:40 UTC
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Brain stimulation study aims to Fine-Tune treatment for movement disorders
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how different patterns of deep brain stimulation (DBS) affect movement and brain activity in people with Parkinson's disease, essential tremor, multiple sclerosis, or dystonia. Researchers will test various stimulation patterns to find which ones work best for…
Matched conditions: DYSTONIA
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 17, 2026 10:26 UTC
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Ultrasound zaps brain without surgery in Parkinson's study
Knowledge-focused OngoingThis study explores whether low-intensity ultrasound can safely and effectively stimulate deep brain areas in people with Parkinson's disease or dystonia. Ten adults who already have implanted deep brain stimulation (DBS) leads will receive ultrasound pulses while researchers rec…
Matched conditions: DYSTONIA
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 08, 2026 12:01 UTC
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Global brain surgery matchmaker aims to solve rare movement mysteries
Knowledge-focused ENROLLING_BY_INVITATIONThis study is not a treatment itself but a global online platform called DBS Matchmaker. It helps doctors from different hospitals share information about patients with rare movement disorders who are getting deep brain stimulation (DBS). The goal is to improve how doctors select…
Matched conditions: DYSTONIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 04, 2026 16:21 UTC