DYSTONIA

This small pilot study tested whether taking a daily zinc supplement for six months is safe and practical for people with GNAO1 disorders, a rare genetic condition that causes movement problems, seizures, and developmental delays. Researchers enrolled 13 participants, aged 6 mont…

This study tested a pill called dipraglurant to see if it could safely reduce the severity and frequency of uncontrollable eyelid spasms (blepharospasm). Fifteen patients who usually get botox injections for the condition took either the drug or a placebo pill. Researchers measur…

This study aimed to understand how two key brain areas—the basal ganglia and cerebellum—interact in people with specific genetic forms of dystonia, a movement disorder. Researchers compared brain scans from 104 participants, including patients with ADCY5 or PRRT2 gene mutations a…

This study aimed to understand how a part of the brain called the cerebellum affects the brain's ability to adapt and learn new movements. Researchers compared 120 people, including healthy volunteers and patients with dystonia, a movement disorder. They used non-invasive brain s…

This study aimed to learn more about how the brain controls movement and what goes wrong in disorders like Parkinson's disease and Tourette's syndrome. Researchers compared over 1,200 healthy volunteers with about 1,000 patients using non-invasive brain scans and tests. The goal …

This study aimed to better understand how the brain controls movement and what causes tremors in conditions like Parkinson's disease and essential tremor. Researchers observed and measured brain activity in 85 participants, including people with tremor and healthy volunteers, usi…

This study aimed to understand what goes wrong in the brains of people with dystonia, a disorder that causes muscles to contract and twist involuntarily. Researchers used MRI and PET brain scans on 31 adults, some with cervical dystonia and some healthy volunteers, to measure a s…

This study aimed to understand how the brain controls movement by comparing eye movements in different patient groups. Researchers tracked eye movements in 14 participants with dystonia, essential tremor, Parkinson's disease, and healthy volunteers. The goal was to see if differe…