DNA METHYLATION
Clinical trials for DNA METHYLATION explained in plain language.
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Spit test could spot oral cancer before it spreads
Diagnosis Recruiting nowThis study is testing whether a simple saliva sample can help diagnose oral squamous cell carcinoma (OSCC), a type of mouth cancer. Researchers will look for specific DNA changes (methylation) in the saliva of 30 patients with OSCC and compare them to 30 healthy controls. If the …
Matched conditions: DNA METHYLATION
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 27, 2026 12:32 UTC
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DNA fingerprinting could solve the mystery of unknown primary cancers
Diagnosis Recruiting nowThis study is testing a new tool that uses DNA methylation patterns to figure out where a cancer started when doctors can't find the original tumor. Researchers will analyze tissue samples from 120 people with cancer of unknown primary. If it works, this could help guide more per…
Matched conditions: DNA METHYLATION
Sponsor: Sun Yat-sen University • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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DNA clues may reveal which esophageal cancers will return soon after surgery
Knowledge-focused Recruiting nowThis study looks at whether changes in DNA methylation—a type of epigenetic marker—can help predict if esophageal cancer will come back soon after surgery. Researchers will analyze tumor tissue from 150 patients who had their cancer removed and track who experiences a recurrence …
Matched conditions: DNA METHYLATION
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Biopsy DNA clues could spare esophageal cancer patients from futile chemo
Knowledge-focused Recruiting nowThis study investigates whether DNA methylation patterns in tumor biopsy samples can predict how well esophageal cancer patients will respond to chemotherapy. Researchers aim to develop a model that identifies patients unlikely to benefit from standard chemo drugs like Fluorourac…
Matched conditions: DNA METHYLATION
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Saliva test may spot lung cancer risk better than smoking history
Knowledge-focused Recruiting nowThis study looks at whether a simple saliva test can find people at high risk for lung cancer more accurately than asking about their smoking history. Researchers will collect saliva from about 1,000 adults aged 50-74 and check for DNA changes linked to smoking. The goal is to cr…
Matched conditions: DNA METHYLATION
Phase: NA • Sponsor: University Hospital, Antwerp • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC