DIFFUSE INTRINSIC PONTINE GLIOMA
Clinical trials for DIFFUSE INTRINSIC PONTINE GLIOMA explained in plain language.
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Engineered immune cells take on childhood brain cancer in first human trial
Disease control Not yet recruitingThis early-phase study tests a new treatment for children and young adults with aggressive brain tumors called high-grade glioma and DIPG. The therapy uses the patient's own immune cells, modified in a lab to better recognize and attack tumor cells. The main goals are to see if t…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE1 • Sponsor: University of Florida • Aim: Disease control
Last updated Jul 02, 2026 02:00 UTC
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Promising drug combo targets aggressive brain cancers in youth
Disease control Not yet recruitingThis study is for adolescents and young adults (ages 12-39) newly diagnosed with aggressive brain tumors called high-grade glioma or DIPG. The goal is to see if a combination of two immunotherapy drugs (relatlimab and nivolumab, sold as Opdualag) is safe and tolerable when given …
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New hope for kids with deadly brain cancer: targeted drug trial launches
Disease control Not yet recruitingThis study tests a drug called tovorafenib in children and young adults (ages 1 to 39) newly diagnosed with aggressive brain tumors (high-grade glioma or DIPG) that have specific genetic changes. The goal is to see if the drug can help them live longer. About 79 participants will…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Experimental drug combo aims to fight deadly brainstem glioma
Disease control Not yet recruitingThis phase 3 trial tests whether adding two experimental drugs (Atengenal and Astugenal) to standard radiation therapy helps people aged 3 and older with a newly diagnosed, aggressive brainstem tumor live longer. About 92 participants will be randomly assigned to get either radia…
Matched conditions: DIFFUSE INTRINSIC PONTINE GLIOMA
Phase: PHASE3 • Sponsor: Burzynski Research Institute • Aim: Disease control
Last updated Jun 26, 2026 18:42 UTC