DEVELOPMENTAL DISABILITY

This study tests whether metformin, a diabetes medication, can help reduce weight gain caused by antipsychotic drugs in adults with intellectual or developmental disabilities. About 100 participants will receive either metformin or a placebo for several months. The goal is to fin…

This study looks at whether a 12-week early intervention program helps improve social communication in children aged 2 to 5 with developmental disorders like autism or intellectual disability. The program involves 12 hours per week of activities either at a center or at home. Res…

This study tests group classes for parents of children aged 0-12 with disruptive behaviors or developmental delays. The program teaches behavior management skills to reduce child behavior problems and parenting stress. About 800 caregivers will participate, and the study measures…

This study tests whether a mixed-reality video game called Bootle Blast can help children aged 6-17 with hemiplegic cerebral palsy improve their arm and hand skills through home practice. About 46 participants will either start the game right away or wait 12 weeks while continuin…

This study looks at whether teaching caregivers how to understand and respond to their child's behavior can reduce problems like aggression or screaming. It includes 9 children (birth to 5 years old) with developmental delays or disabilities who show challenging behaviors. Caregi…

This study aims to understand how brain damage from strokes, tumors, or diseases affects thinking skills. Researchers will use brain scans and memory tests in 400 people with brain injuries and healthy volunteers. The goal is to learn which brain areas are responsible for specifi…

This study looks at a special clinic designed to help adults with conditions like cerebral palsy, spina bifida, or developmental disabilities get better, ongoing care. Many of these people face a "cliff" when they leave children's healthcare and struggle to find adult doctors who…

This study looks at how a robotic walking trainer (Trexo) helps people with physical disabilities like cerebral palsy. Researchers want to understand how different robot modes—like full assistance or requiring some effort—affect heart rate, steps, and brain activity. About 50 par…

This study tests whether a one-time online lesson can improve how researchers think about and include people with disabilities in their studies. About 200 researchers will take the course, and their knowledge and attitudes will be measured before and after. The goal is to make re…

This study is testing whether hand and arm assessments for children with cerebral palsy can be done effectively through video calls instead of in-person visits. About 100 children aged 6 to 17 will try virtual tests at home, and researchers will compare the results to in-person a…