DENGUE FEVER

This study tested a dengue vaccine (TDV) in 187 healthy Japanese volunteers aged 4 to 60. Participants received two shots three months apart. The main goal was to see if the vaccine triggers an immune response against all four types of dengue virus. The trial is now complete.

This phase 2 trial tested a tetravalent dengue vaccine (TDV) in 30 healthy adults, some with prior dengue exposure and some without. The goal was to measure the body's immune response and check for safety. Participants received a single shot, and researchers tracked antibody leve…

This study tested a clever way to prevent dengue fever: releasing mosquitoes infected with Wolbachia bacteria into neighborhoods in Brazil. Over four years, researchers compared areas that got these special mosquitoes plus usual control methods to areas with usual methods alone. …

This study followed 775 healthy children aged 2-9 in Cambodia over three years to learn how mosquitoes spread dengue and other viruses. Researchers took blood samples every wet and dry season to check for past or current infections. The goal was to understand why young children g…

This study looked at 150 people with dengue fever to see if abdominal ultrasound findings, like gallbladder thickening or fluid in the belly, are linked to low platelet counts—a sign of severe disease. Researchers reviewed medical records and ultrasound images to find patterns th…

This completed study tested whether machine learning could predict dengue and severe dengue using electronic health records from 1,000 patients in Thailand and Vietnam. The goal was to create a low-cost tool that works even when lab tests are unavailable. Researchers used vital s…