CYTOMEGALOVIRUS INFECTIONS

This study tested a new vaccine against cytomegalovirus (CMV), a common virus that can cause serious problems in newborns and people with weak immune systems. The vaccine was given to 339 healthy adults aged 18 to 50 to see if it was safe and triggered a strong immune response. R…

This study tested a vaccine called Triplex in 90 adults who have both HIV and cytomegalovirus (CMV). The goal was to see if the vaccine is safe and boosts the immune system's ability to fight CMV. Participants received either the vaccine or a placebo, and researchers monitored th…

This early-phase study tested a new vaccine called SPYVLP01 designed to prevent cytomegalovirus (CMV) infection. Researchers gave the vaccine to 120 healthy adults aged 18-50 to check its safety and how well it triggers an immune response. The vaccine was tested with and without …

This study looked at whether giving HIV-infected infants (aged 1 month to 1 year) early treatment for two common infections—cytomegalovirus (CMV) and tuberculosis (TB)—could help them survive severe pneumonia. Over 560 babies participated across multiple hospitals. The goal was t…

This study tested whether giving special immune cells (T cells) that target CMV or adenovirus could help control these infections in people who had a stem cell transplant. Sixteen children and adults with persistent or drug-resistant infections received the cells. The main goal w…

This study looked at a new blood test that detects a tiny piece of the CMV virus (called microRNA) in people who had a stem cell transplant. The goal was to see if this test works as well as the standard test for finding CMV reactivation. Researchers used stored blood samples fro…

This study followed 400 stem cell transplant recipients to see how well newer anti-CMV drugs work in everyday practice and whether the virus becomes resistant. Researchers tracked infections, drug side effects, and survival. The goal is to improve treatment guidelines for high-ri…