New CMV vaccine candidate passes first safety check in healthy volunteers

NCT ID NCT06145178

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 27 times

Summary

This early-phase study tested a new vaccine called SPYVLP01 designed to prevent cytomegalovirus (CMV) infection. Researchers gave the vaccine to 120 healthy adults aged 18-50 to check its safety and how well it triggers an immune response. The vaccine was tested with and without adjuvants (boosters) to find the best formulation.

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Contacts and locations

Locations

  • Medicines Evaluation Unit

    Manchester, United Kingdom

  • Velocity Bristol

    Bristol, United Kingdom

Conditions

Explore the condition pages connected to this study.