CYTOMEGALOVIRUS INFECTION
Clinical trials for CYTOMEGALOVIRUS INFECTION explained in plain language.
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Can 'Supercharged' donor cells beat viruses that drugs Can't?
Disease control Recruiting nowThis study tests whether giving patients special donor immune cells (called CD45RA-depleted DLI) can treat viral infections that persist after a stem cell transplant. The trial involves 30 participants who have not improved with standard antiviral drugs. Researchers will measure …
Matched conditions: CYTOMEGALOVIRUS INFECTION
Phase: PHASE1, PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Blood test may let transplant patients stop virus meds earlier
Disease control Recruiting nowThis study looks at whether stem cell transplant patients can safely stop taking a medicine called letermovir earlier if their immune system shows a strong response to CMV. About 105 participants will be monitored to see if this approach reduces infections and side effects compar…
Matched conditions: CYTOMEGALOVIRUS INFECTION
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Banked immune cells show promise against Life-Threatening viruses in transplant patients
Disease control Recruiting nowThis early-phase study tests whether specially trained immune cells from healthy donors can safely treat viral infections (EBV, CMV, adenovirus, BK virus) in patients who have had a stem cell transplant or certain CAR-T therapy. These infections can be life-threatening when the i…
Matched conditions: CYTOMEGALOVIRUS INFECTION
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Donor immune cells take on tough viruses in transplant patients
Disease control Recruiting nowThis early-stage trial tests whether specially grown immune cells from a donor can safely help transplant patients fight off viral infections that standard treatments can't control. The cells target Epstein-Barr virus, cytomegalovirus, adenovirus, and BK virus. Up to 36 adults wh…
Matched conditions: CYTOMEGALOVIRUS INFECTION
Phase: PHASE1 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Personalized CMV prevention could cut infections in kidney transplant patients
Disease control Recruiting nowThis study compares two ways to prevent cytomegalovirus (CMV) infection in kidney transplant patients who already carry the virus. One approach gives antiviral drugs to everyone for 3 months, while the other uses immune system tests to decide who needs treatment. The goal is to s…
Matched conditions: CYTOMEGALOVIRUS INFECTION
Phase: PHASE3 • Sponsor: University Hospital, Rouen • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New drug combo aims to beat CMV in kidney transplants
Disease control Recruiting nowThis study tests whether adding letermovir to the standard drug valganciclovir works better than valganciclovir alone for treating CMV infections in kidney transplant recipients. About 80 adults who have a kidney transplant and a CMV infection will take part. The goal is to see i…
Matched conditions: CYTOMEGALOVIRUS INFECTION
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Donor immune cells show promise against dangerous viruses in vulnerable patients
Disease control Recruiting nowThis study tests whether specially grown immune cells from an unrelated donor can safely treat viral infections in people with weakened immune systems, such as after a stem cell transplant. About 750 participants will receive these cells and be monitored for side effects like inf…
Matched conditions: CYTOMEGALOVIRUS INFECTION
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Supercharged donor cells take on viruses after transplant
Disease control Recruiting nowThis study tests whether specially grown donor immune cells (viral-specific T-cells) can safely treat viral infections that often occur after a stem cell transplant. These infections can be serious and sometimes don't respond to standard antiviral drugs. The approach aims to boos…
Matched conditions: CYTOMEGALOVIRUS INFECTION
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New study aims to uncover hidden burden of CMV in young transplant patients
Knowledge-focused Recruiting nowThis study reviews medical records of 230 children in Italy who received a stem cell transplant between 2018 and 2020. Researchers want to understand how common and costly cytomegalovirus (CMV) reactivation is in these young patients. The goal is to give doctors and health offici…
Matched conditions: CYTOMEGALOVIRUS INFECTION
Sponsor: MSD Italia S.r.l. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC