Donor immune cells show promise against dangerous viruses in vulnerable patients
NCT ID NCT02532452
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether specially grown immune cells from an unrelated donor can safely treat viral infections in people with weakened immune systems, such as after a stem cell transplant. About 750 participants will receive these cells and be monitored for side effects like infusion reactions or graft-versus-host disease. The goal is to see if the cells can control the virus without causing serious harm.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Akron Children's Hospital
RECRUITINGAkron, Ohio, 44308, United States
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
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The Ohio State University Wexner Medical Center - James Cancer Hospital
RECRUITINGColumbus, Ohio, 43210, United States
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University of Cincinnati Medical Center
COMPLETEDCincinnati, Ohio, 45219, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can cord blood t cells be trained to stop viral infections after transplant?
- Can a new IV antiviral tame two stubborn viruses?
- Can specially grown immune cells from donors beat viruses that won't go away?
- A new drug combo may shield kidney transplant patients from a common viral threat
- Blood test could tailor CMV prevention after stem cell transplants
- Scientists compare immune responses to viral and bacterial infections in ICU patients