Banked immune cells show promise against Life-Threatening viruses in transplant patients
NCT ID NCT04013802
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests whether specially trained immune cells from healthy donors can safely treat viral infections (EBV, CMV, adenovirus, BK virus) in patients who have had a stem cell transplant or certain CAR-T therapy. These infections can be life-threatening when the immune system is weak. The cells are pre-made and stored in a bank, so they are ready to use right away. The main goal is to check safety and see if the cells reduce virus levels.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Houston Methodist Hospital
RECRUITINGHouston, Texas, 77003, United States
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Texas Children's Hospital
RECRUITINGHouston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can cord blood t cells be trained to stop viral infections after transplant?
- Can a new IV antiviral tame two stubborn viruses?
- Can specially grown immune cells from donors beat viruses that won't go away?
- A new drug combo may shield kidney transplant patients from a common viral threat
- Blood test could tailor CMV prevention after stem cell transplants
- Scientists compare immune responses to viral and bacterial infections in ICU patients