Donor immune cells take on tough viruses in transplant patients
NCT ID NCT05183490
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests whether specially grown immune cells from a donor can safely help transplant patients fight off viral infections that standard treatments can't control. The cells target Epstein-Barr virus, cytomegalovirus, adenovirus, and BK virus. Up to 36 adults who have had a stem cell or organ transplant will receive an infusion of these cells, and researchers will watch closely for side effects like graft-versus-host disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Rapidly generated virus specific T (R-MVST) cells
What this could lead to
If it works, this could offer a new treatment option for transplant patients with viral infections that don't respond to standard care.
What could go wrong
This is a very early Phase 1 trial with only 36 participants, focused on safety. The treatment may cause serious side effects like graft-versus-host disease, and it's too soon to know if it effectively controls infections.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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