COLORECTAL ADENOMA

This study tests a vaccine designed to help the immune system target and destroy abnormal colon growths called advanced adenomas, which can turn into cancer. About 110 people who recently had these high-risk polyps removed will receive either the MUC1 vaccine or a placebo. The go…

This study tests whether linaclotide, a drug that helps the intestines release water and salt, can slow or prevent colorectal cancer. About 230 people with colorectal adenomas (precancerous growths) or early-stage colorectal cancer will take the drug or a placebo before surgery. …

This study tests a computer program that helps doctors analyze images from colonoscopies. The software automatically finds growths in the colon and gives a probability of whether they are adenomas (precancerous) or non-adenomas (benign). The goal is to see if the tool improves ho…

This study aims to see how well the LifeKit Prevent test finds colorectal cancer and precancerous polyps using a stool sample. About 12,000 adults aged 40 and older getting a routine screening colonoscopy will provide samples. The goal is to check if the test is accurate enough t…

This study looks at whether taking aspirin on an intermittent schedule can help prevent colorectal cancer in people who have had colorectal adenomas (precancerous polyps). Researchers will measure changes in cell growth and death markers in the colon lining. The study involves 81…

This study looks at tissue samples from 582 people with colon cancer, colon polyps, or healthy colons to find molecular markers linked to cancer development. Researchers are testing for gene mutations, protein changes, and gut bacteria differences. The goal is to better understan…