COAGULOPATHY

This study tested a freeze-dried plasma product that can be mixed with water in 6 minutes, avoiding the long thaw time of standard plasma. It included 42 trauma patients with severe bleeding who needed blood transfusions. The goal was to see if faster plasma delivery could improv…

This study tests whether a special donor plasma product called OctaplasLG can help people with septic shock who develop blood clotting problems. Sixty participants will receive either OctaplasLG or a placebo (salt water) to see if the treatment improves clotting and outcomes. The…

This study looked at whether giving whole blood (all blood parts together) works as well as giving separate blood parts (red cells, plasma, platelets) to people with severe bleeding from trauma. About 200 patients who needed a massive transfusion were included. The goal was to se…

This early study tested the safety of a new spray-dried plasma product called FrontlineODP in 24 healthy volunteers. Participants received increasing doses (1 to 4 units) to see if it causes side effects. The goal is to develop a shelf-stable plasma that can be stored at room tem…

This study looked at 150 adults with sepsis in the ICU to see if low magnesium levels are connected to blood clotting problems. Researchers measured magnesium and clotting markers at admission and tracked outcomes like DIC and survival. The goal was to understand if magnesium cou…

This completed study looked at 30 adults with sepsis to understand how changes in tiny blood vessels (microcirculation) relate to blood clotting problems. Researchers used a special microscope to view blood vessels under the tongue and measured clotting factors. The goal was to s…