Scientists watch sepsis damage tiny vessels in real time

NCT ID NCT07404475

Completed Knowledge-focused Sponsor: Università Politecnica delle Marche Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 30 adults with sepsis to understand how changes in tiny blood vessels (microcirculation) relate to blood clotting problems. Researchers used a special microscope to view blood vessels under the tongue and measured clotting factors. The goal was to see if patients with clotting issues had worse vessel damage. No treatments were given; this was purely an observation study.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand how sepsis damages small blood vessels and causes clotting issues, potentially guiding future treatments.
What could go wrong: This is a small, observational study with only 30 participants. It does not test any treatment, so it cannot directly improve patient care. Results may not apply to all sepsis patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

blood coagulation disease infectious disease with sepsis Sepsis vascular hemostatic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COAGULOPATHY SEPSIS

Contacts and locations

Locations

Azienda Ospedaliero Universitaria delle Marche

Ancona, 60126, Italy

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