CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Clinical trials for CLINICAL STAGE IV GASTRIC CANCER AJCC V8 explained in plain language.
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Major cancer trial tests if adding one drug helps patients live longer
Disease control Recruiting nowThis large, late-stage trial is testing which of two chemotherapy combinations works better for people with advanced stomach or esophageal cancer that has spread and cannot be removed by surgery. About 382 participants will be randomly assigned to receive either the standard two-…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New hope for Tough-to-Treat cancers: adding immune booster to standard care
Disease control Recruiting nowThis study is for people with advanced stomach or esophageal cancer that has worsened after initial treatment. It tests if adding an immunotherapy drug called nivolumab to the standard two-drug chemotherapy helps control the cancer better and helps patients live longer. About 224…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New trial tests if switching PARP inhibitors can help control advanced cancers
Disease control Recruiting nowThis study is testing whether the drug talazoparib can help control advanced cancers in patients whose tumors have specific mutations in genes that help repair DNA damage. It is enrolling 36 adults with various advanced solid tumors (like breast, ovarian, prostate, pancreatic, an…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Scientists test 'One-Two Punch' against Tough-to-Treat cancers
Disease control Recruiting nowThis early-stage study is testing the safety and best dose of a new two-drug combination for people with advanced solid tumors that have a specific marker called HER2. The treatment pairs an existing targeted cancer drug with a new pill that aims to block cancer cells' ability to…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Spray-On chemo: new hope for Tough-to-Treat abdominal cancers?
Disease control Recruiting nowThis early-stage study is testing the safety of a new, minimally invasive procedure called PIPAC. It delivers chemotherapy as a fine mist directly into the abdomen for people with advanced ovarian, uterine, stomach, colon, or appendix cancers that have spread to the abdominal lin…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Scientists test 'Double Punch' drug combo for Tough-to-Treat stomach cancers
Disease control Recruiting nowThis early-stage study is testing the safety and best dose of a new two-drug combination for people with advanced cancers that have a specific marker called HER2. The trial focuses on stomach and gastroesophageal junction cancers that have spread or cannot be removed by surgery, …
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New drug duo tested for Tough-to-Treat stomach cancers
Disease control Recruiting nowThis early-stage study is testing whether combining two existing drugs, pembrolizumab and lenvatinib, can help control advanced stomach or gastroesophageal cancers that have spread or cannot be surgically removed. The trial is for adults whose cancer has continued to grow despite…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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New attack on advanced stomach cancer: boosting immune system in the abdomen
Disease control Recruiting nowThis early-stage study is testing whether adding an immune-boosting drug directly into the abdomen, along with standard immunotherapy and chemotherapy, can better treat stomach cancer that has spread to the abdominal lining. The goal is to see if this combination can reduce the a…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Custom-Made vaccine aims to train immune system to fight advanced cancers
Disease control Recruiting nowThis study is testing a new, personalized vaccine designed to target the unique proteins on a patient's own cancer cells. It is being given alongside an existing immunotherapy drug (pembrolizumab) to see if the combination is safe and can help control advanced solid tumors that h…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Can a simple ear tap fight cancer weight loss?
Symptom relief Recruiting nowThis study is testing if a simple, non-invasive therapy called ear acupressure can help improve appetite and prevent weight loss in people with certain advanced cancers. Researchers will recruit 66 patients with stomach, esophageal, or pancreatic cancer to see if applying small a…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Mar 12, 2026 13:52 UTC
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Scientists watch Cancer's blood supply live during surgery
Knowledge-focused Recruiting nowThis study aims to learn more about the tiny blood vessels that feed solid tumors. Researchers will use a special microscope during a patient's standard cancer surgery to see these vessels in real time. The goal is to understand how tumor blood flow works and if it relates to how…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists build a living library of cancer to unlock treatment secrets
Knowledge-focused Recruiting nowThis study is collecting tissue and blood samples from cancer patients over time to create a research resource called a biobank. Researchers will analyze these samples to understand how cancer changes during treatment and why some treatments stop working. The goal is to help scie…
Matched conditions: CLINICAL STAGE IV GASTRIC CANCER AJCC V8
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Mar 17, 2026 13:09 UTC