CHRONIC SPONTANEOUS URTICARIA (CSU)

This study tests two experimental drugs, remibrutinib (a pill) and dupilumab (an injection), in adults with chronic hives that antihistamines can't control. About 400 participants will receive one of the treatments for 4 weeks to see which works faster at reducing itch and hives.…

This study follows 225 adults with chronic spontaneous urticaria (hives) or allergic asthma whose disease is well-controlled on a standard biologic drug. Their doctor has decided to switch them to a biosimilar called Omlyclo®. The main goal is to see if they stay stable for 12 mo…

This study tests a new drug called lesigercept for people with chronic spontaneous urticaria (long-term hives) that antihistamines don't fully control. About 150 adults will receive either the drug or a placebo for 12 weeks to see if it reduces itching and welts. The goal is to f…

This study tests a new medicine called ICP-332 for people with moderate to severe chronic hives (urticaria) that don't get better with standard allergy pills. The goal is to see if it reduces itching and welts better than a placebo. About 344 adults aged 18 to 75 will take part o…

This study tests an experimental drug called CM512 for people with chronic spontaneous urticaria (CSU) — long-lasting hives and itching that don't go away with standard antihistamines. About 48 adults will receive either CM512 or a placebo injection. The main goal is to see if th…

This study looks at different forms of IgE, an immune protein involved in allergies, in healthy volunteers and people with conditions like severe allergic reactions, chronic hives, mastocytosis, and certain immune deficiencies. By comparing these groups, researchers hope to learn…