CHRONIC RHINOSINUSITIS (DIAGNOSIS)

This study tests whether rinsing the nose with a xylitol solution can reduce sinus symptoms in adults with cystic fibrosis. Participants will use both xylitol and standard saline rinses at different times to compare effects. The goal is to see if xylitol, a natural sugar alcohol,…

This pilot study tests whether adding epinephrine to a standard nerve block (pterygopalatine ganglion block) reduces bleeding during functional endoscopic sinus surgery (FESS) in people with chronic rhinosinusitis. Eighty adults undergoing bilateral FESS will receive the nerve bl…

This study investigates why some people develop chronic sinusitis with nasal polyps, focusing on how epigenetic changes and viruses might trigger the disease. Researchers will analyze tissue samples from 60 participants, including patients with active disease, those in remission,…

This study was designed to see how chronic sinusitis affects the tiny hair-like cells (cilia) that help clear mucus from the nose. Researchers planned to use special glowing nano-sticks to measure how well these cells work. However, the study was withdrawn before any participants…

This study looks at the bacteria living in the nose and sinuses of people with chronic sinusitis, allergies, and healthy individuals. By analyzing tissue samples from 285 participants, researchers hope to identify which bacteria are linked to long-term inflammation. The goal is t…