CHRONIC RHINOSINUSITIS (DIAGNOSIS)

This study looks at whether adding epinephrine to a nerve block behind the cheek can lessen bleeding during sinus surgery for people with chronic sinusitis. About 80 adults will take part. The goal is to see if this approach makes the surgery cleaner and potentially safer.

This study tests whether rinsing the nose with a solution containing xylitol (a sugar alcohol) can reduce sinus symptoms in people with cystic fibrosis. About 38 adults will use both xylitol rinses and standard saltwater rinses at different times to compare effects. The goal is t…

This study was designed to see how chronic sinusitis affects the tiny hairs (cilia) that help clear mucus from the nose. Researchers planned to use glowing nano-sized sticks to measure cilia movement in adults having sinus surgery. However, the study was withdrawn before enrollin…

This study looks at why some people get a severe form of sinusitis with nasal polyps that doesn't go away easily. Researchers think changes in how genes are turned on or off (epigenetics) and certain viruses might be the cause. They will compare tissue samples from 60 people—thos…

This study looks at the bacteria living in the nose and sinuses of people with chronic sinusitis, allergies, or healthy sinuses. Researchers want to see if certain bacteria cause inflammation that leads to long-term sinus problems. The goal is to gather basic knowledge that could…