CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Clinical trials for CHRONIC RHINOSINUSITIS (DIAGNOSIS) explained in plain language.
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Good bacteria rinse may tame stubborn sinus trouble
Symptom relief Recruiting nowThis study tests whether rinsing the sinuses with a probiotic (good bacteria) solution can reduce symptoms of chronic sinusitis better than a plain saltwater rinse. About 60 adults who have had sinus surgery in the past will use the rinse daily for a period and report changes in …
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Phase: PHASE2 • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Could a cystic fibrosis drug ease stubborn sinus infections?
Symptom relief Recruiting nowThis early study tests whether ivacaftor, a drug used for cystic fibrosis, can help people with chronic sinusitis caused by hard-to-treat bacteria. Twenty adults will receive either ivacaftor plus standard care or standard care alone for 14 days. Researchers will check safety, sy…
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Phase: EARLY_PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New study tracks sinus health in kids with cystic fibrosis on breakthrough drugs
Knowledge-focused Recruiting nowThis study follows 80 children aged 2-8 with cystic fibrosis to see how highly effective CF drugs (Kalydeco or Trikafta) impact sinus disease and sense of smell. Researchers will use MRI scans, smell tests, and quality-of-life surveys over two years. The goal is to understand whe…
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Can sinus surgery help cystic fibrosis lungs? new study investigates
Knowledge-focused Recruiting nowThis study follows 170 adults with cystic fibrosis and chronic sinusitis to see if sinus surgery improves lung function and quality of life compared to medical treatment alone. Participants either have surgery or continue with standard care. Researchers will track changes in brea…
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Scientists probe Mepolizumab's effect on nasal cell health
Knowledge-focused Recruiting nowThis early lab study from Johns Hopkins University examines how mepolizumab (Nucala) affects the health and function of nasal cells from people with chronic sinusitis and nasal polyps. Researchers will measure changes in inflammation markers and cell barrier integrity. Only 8 par…
Matched conditions: CHRONIC RHINOSINUSITIS (DIAGNOSIS)
Phase: EARLY_PHASE1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC