CHRONIC RENAL FAILURE

This study compared two types of dialysis in 415 older adults (ages 65-90) with chronic kidney failure: online hemodiafiltration and conventional hemodialysis. The goal was to see which method is better tolerated and whether it reduces heart problems and other complications. Pati…

This study tested a special dialysis fluid called icodextrin in 439 adults with chronic kidney failure who use peritoneal dialysis at home. The goal was to see if it works better than standard glucose solutions for overnight exchanges and to check for side effects. Researchers tr…

This study tested a new dialysis filter called ELISIO-HX in 22 adults with kidney failure. Participants used the new filter three times a week for 12 weeks. The goal was to see if it safely maintained albumin levels while improving removal of certain waste products. The trial is …

This study tested whether sevelamer carbonate, a drug that binds phosphate in the gut, can lower levels of a hormone called FGF-23 in people with chronic kidney disease (CKD) who are not yet on dialysis. The trial included 98 adults with moderate to severe CKD and high FGF-23 lev…

This study looked at tiny particles called extracellular vesicles found in urine to see if they can help tell the difference between healthy kidneys and chronic kidney disease. Researchers measured these particles in 143 people, including healthy volunteers and patients with kidn…

This completed Phase 2 study investigated how the drugs dapagliflozin and balcinrenone, alone or together, affect the body's handling of water and salts in people over 50 with stage 3 chronic kidney disease. Over 28 days, 103 participants took daily pills to measure changes in ur…

This study tested whether home automation and remote monitoring can help elderly people (65+) with multiple chronic conditions live safely at home. Over 500 participants had their homes equipped with sensors that tracked health signs and sent alerts to doctors. The main goal was …

This completed study observed 178 patients with advanced cancer, chronic kidney failure, or chronic lung diseases to assess their palliative care needs and survival factors. Researchers used two scoring tools to evaluate when and how to best introduce palliative care alongside re…

This study looked at 225 adults with a rare, inherited form of kidney disease to find the genetic causes. Participants had chronic kidney failure and often had a family history of gout. Researchers tested for known gene mutations and searched for new ones in families without a cl…