CHRONIC RENAL FAILURE

This study tested a drug called sevelamer carbonate in 98 people with chronic kidney disease (stages 3b-4) who were not yet on dialysis. The goal was to see if the drug could lower a blood marker called FGF-23, which is linked to bone and heart problems. Participants took either …

This study checked how safe and effective icodextrin, a special dialysis fluid, is for people with chronic kidney failure who use peritoneal dialysis. Researchers looked at 439 patients to see if icodextrin helped prevent treatment failure or death compared to standard glucose so…

This study tested a new dialysis filter called ELISIO-HX in 22 adults with kidney failure. The main goal was to see if the filter was safe by checking that it did not lower blood albumin levels. The study also looked at how well the filter removed certain waste products from the …

This study looked at tiny particles called extracellular vesicles found in urine. Researchers compared 143 healthy adults and people with chronic kidney failure to find normal and abnormal levels of these particles. The goal was to see if these particles could help track kidney d…

This study looked at 178 people with advanced cancer, chronic kidney disease, or serious lung conditions to find out when they need palliative care. Researchers used special scores to predict survival and guide care. No new treatments were tested; instead, the goal was to learn h…

This study looked at how two medications—dapagliflozin and balcinrenone—affect the way the body manages water, salt, and energy in people over 50 with stage 3 chronic kidney disease. Over 100 participants took one of four treatments (dapagliflozin alone, balcinrenone alone, both,…

This study aims to find the genetic causes of a rare, inherited kidney disease called HTIN. Researchers will study 225 adults with the condition and their families to look for specific gene mutations. The goal is to better understand the disease, not to test a new treatment.