CHRONIC GRAFT VERSUS HOST DISEASE
Clinical trials for CHRONIC GRAFT VERSUS HOST DISEASE explained in plain language.
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New drug combo for GVHD shows promise but trial ends early
Disease control TerminatedThis study looked at whether adding the drug itacitinib to standard steroid treatment could help people with moderate to severe chronic graft-versus-host disease (cGVHD), a complication after a stem cell transplant. The goal was to control the disease, not cure it. The trial was …
Matched conditions: CHRONIC GRAFT VERSUS HOST DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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Early ruxolitinib shows promise in cutting steroids for young GVHD patients
Disease control TerminatedThis study tested whether giving the drug ruxolitinib right away, instead of starting with high-dose steroids, could help children and young adults with chronic graft-versus-host disease (cGVHD) after a stem cell transplant. Only one person enrolled before the study was stopped e…
Matched conditions: CHRONIC GRAFT VERSUS HOST DISEASE
Phase: PHASE1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated May 04, 2026 16:31 UTC