CHRONIC FATIGUE SYNDROME
Clinical trials for CHRONIC FATIGUE SYNDROME explained in plain language.
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Could fluvoxamine and metformin beat long COVID fatigue?
Symptom relief CompletedThis completed Phase 3 trial tested whether two widely available drugs—fluvoxamine (an antidepressant) and metformin (a diabetes drug)—can reduce fatigue and other symptoms in people with long COVID. 399 adults with confirmed prior COVID-19 infection and persistent symptoms took …
Matched conditions: CHRONIC FATIGUE SYNDROME
Phase: PHASE3 • Sponsor: Cardresearch • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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New hope for women with vestibulodynia: cream and pill combo under study
Symptom relief CompletedThis study tested two treatments for vestibulodynia, a chronic pain condition affecting the vulvar area. 209 women received either a lidocaine/estradiol cream, the antidepressant nortriptyline, both, or a placebo. The goal was to see which approach best reduces pain and improves …
Matched conditions: CHRONIC FATIGUE SYNDROME
Phase: PHASE2 • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Herbal blend shows promise for chronic fatigue in new trial
Symptom relief CompletedThis completed Phase 4 trial tested two herbal granules, Compound Ciwujia and Guipi, in 235 adults with chronic fatigue syndrome. Participants took the granules for 6 weeks. The main goal was to see if fatigue scores improved. The study also looked at quality of life and traditio…
Matched conditions: CHRONIC FATIGUE SYNDROME
Phase: PHASE4 • Sponsor: Heilongjiang Quanle Pharmaceutical Co., Ltd. • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Could a common ADHD drug ease chronic fatigue brain fog?
Symptom relief CompletedThis study tested whether lisdexamfetamine dimesylate (Vyvanse), a drug used for ADHD, can help with cognitive impairment and fatigue in adults with chronic fatigue syndrome. Twenty-six participants were randomly assigned to receive either Vyvanse or a placebo for six weeks. The …
Matched conditions: CHRONIC FATIGUE SYNDROME
Phase: PHASE4 • Sponsor: Rochester Center for Behavioral Medicine • Aim: Symptom relief
Last updated Jun 26, 2026 14:45 UTC
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Study probes heart and lung function in ME/CFS to unravel Post-Exertion crash
Knowledge-focused CompletedThis study looked at heart and lung function in 106 people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) to better understand post-exertional malaise—the severe worsening of symptoms after physical activity. Participants did two maximal exercise tests on consec…
Matched conditions: CHRONIC FATIGUE SYNDROME
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC