CAROTID ARTERY STENOSIS

This trial tests whether using a balloon guide catheter along with a filter can better protect the brain during carotid artery stenting. People with narrowed neck arteries (carotid stenosis) who need stenting are randomly assigned to get either the balloon-plus-filter combo or a …

This study tests a stent (Carotid WALLSTENT) used with a special brain protection system (ENROUTE NPS) in 60 Chinese patients with narrowed carotid arteries. The goal is to see if the combination can be safely delivered to prevent strokes. Patients must have significant artery na…

This study tests a new device that uses sound waves (lithotripsy) to break up hard calcium deposits in the carotid arteries of the neck before placing a stent. About 185 people with heavily calcified carotid arteries will be enrolled. The main goal is to see if the procedure is s…

This study tests a new type of catheter (a thin tube) designed to make carotid artery stenting easier and safer when done through the wrist. About 204 people with blocked neck arteries will be randomly assigned to get the new catheter or a standard one. The main goal is to see if…

This study tests a new device called SwitchGuard NPS that is designed to catch loose debris and protect the brain during a procedure to open narrowed neck arteries. About 103 people with carotid artery stenosis who are at high risk for standard surgery will receive the device alo…

This study tests whether adding the drug dexmedetomidine during carotid artery surgery helps keep blood pressure more stable. About 44 adults having this surgery will be randomly assigned to receive either standard anesthesia alone or standard anesthesia plus dexmedetomidine. The…

This study looks at two common anesthetics used during carotid artery surgery to see which one better protects the brain from small areas of damage. About 160 adults having planned carotid surgery will get either an intravenous or inhaled anesthetic. Researchers will compare brai…