CARDIAC FAILURE

This study tests whether social prescribing—connecting patients to community resources for issues like housing, income, or loneliness—can help women with heart failure better adhere to their medications and improve their quality of life. Researchers will enroll 200 women across f…

This study tests if adding the drug landiolol to the fluid that protects the heart during mitral valve surgery can reduce a serious complication called low cardiac output syndrome, where the heart struggles to pump enough blood after surgery. About 1500 adults having elective mit…

This study is testing a small device called the MiniLung petite kit, which helps oxygenate blood and remove carbon dioxide in newborns and children weighing 2 to 8 kilograms who have severe breathing or heart failure. The device works with a console to temporarily take over the w…

This study is looking for tiny molecules in the blood called microRNAs that can help doctors tell if a heart transplant patient's immune system is too active (causing rejection) or too weak (causing infection). Researchers will follow 250 adult heart transplant recipients for one…

This study is looking at tiny molecules called microRNAs in the blood of children who have had a heart transplant. The goal is to find patterns that can predict which children are at risk for infection or rejection of the new heart. By understanding these patterns, doctors hope t…

This study will use cardiac MRI to track changes in heart structure and function in 40 patients who have had endovascular repair for aortic disease. Researchers will compare heart measurements taken before surgery and again at 6 and 12 months afterward. The goal is to understand …

This study looks at how different types of platelets change in patients on ECMO, a machine that helps the heart and lungs. Researchers will track 75 adults in intensive care to see if shifts in platelet populations relate to bleeding or clotting problems. The goal is to better un…

This study follows 100 adults who needed ECMO support for severe heart or lung failure. Researchers will track muscle size, strength, and quality of life over time to understand why some patients develop lasting weakness. No new treatments are being tested; the goal is to gather …