CARCINOMA, SQUAMOUS CELL
Clinical trials for CARCINOMA, SQUAMOUS CELL explained in plain language.
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Experimental drug aims to supercharge immune system before cancer surgery
Disease control CompletedThis early-phase study tested a single dose of an experimental antibody (MEDI0562) given before surgery to 13 patients with advanced head and neck cancer or melanoma. The goal was to see if the drug safely activates the immune system to fight the cancer. Researchers compared givi…
Matched conditions: CARCINOMA, SQUAMOUS CELL
Phase: PHASE1 • Sponsor: Providence Health & Services • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Lung cancer trial matches drugs to genes: a step toward personalized treatment
Disease control CompletedThis trial tested several targeted drugs in people with non-small cell lung cancer whose tumors had specific genetic changes. The goal was to see if these drugs could shrink tumors or delay cancer growth. Over 400 participants received treatment based on their tumor's genetic pro…
Matched conditions: CARCINOMA, SQUAMOUS CELL
Phase: PHASE2 • Sponsor: University of Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Immunotherapy drug shows promise in preventing High-Risk skin cancer recurrence
Disease control CompletedThis study tested whether the immunotherapy drug pembrolizumab (Keytruda) could help prevent skin cancer from returning in people with high-risk locally advanced squamous cell carcinoma who had already undergone surgery and radiation. About 450 participants were randomly assigned…
Matched conditions: CARCINOMA, SQUAMOUS CELL
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Smarter radiation dosing aims to cut side effects for head and neck cancer patients
Disease control CompletedThis study tested a new way of giving radiation to people with head and neck cancer. The goal was to lower the radiation dose to healthy neck areas to reduce side effects like trouble eating, while still keeping the cancer from coming back. About 300 patients took part, and the r…
Matched conditions: CARCINOMA, SQUAMOUS CELL
Phase: PHASE3 • Sponsor: Radboud University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Smoking and drinking leave genetic marks in mouth cells that may lead to cancer
Knowledge-focused CompletedThis study looked at 100 healthy adults to see how tobacco and alcohol use cause genetic changes in cells lining the mouth. Researchers collected cheek cells using a gentle brush and searched for mutations linked to oral cancer. The goal was to understand how these substances mig…
Matched conditions: CARCINOMA, SQUAMOUS CELL
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC