BRONCHIOLITIS OBLITERANS
Clinical trials for BRONCHIOLITIS OBLITERANS explained in plain language.
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Inhaled therapy tested to fight lung transplant rejection
Disease control CompletedThis study tested whether adding an inhaled form of the drug cyclosporine (L-CsA) to standard care could better preserve lung function in adults who had received a double lung transplant and developed chronic rejection (CLAD-BOS). 169 participants were randomly assigned to receiv…
Matched conditions: BRONCHIOLITIS OBLITERANS
Phase: PHASE3 • Sponsor: Zambon SpA • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Inhaled therapy tested to halt lung transplant failure
Disease control CompletedThis study tested whether adding an inhaled form of the drug cyclosporine (L-CsA) to standard care could better treat chronic rejection in single lung transplant patients. 62 adults who had received a transplant at least a year prior and were experiencing declining lung function …
Matched conditions: BRONCHIOLITIS OBLITERANS
Phase: PHASE3 • Sponsor: Zambon SpA • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New scan could catch silent lung rejection years earlier
Diagnosis CompletedThis study tested a new type of MRI scan using a special gas to see if it can detect early signs of a serious complication called BOS in people who have had a lung transplant. BOS is a form of chronic rejection that affects over half of transplant recipients who survive five year…
Matched conditions: BRONCHIOLITIS OBLITERANS
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Diagnosis
Last updated Mar 30, 2026 14:30 UTC
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Researchers track hidden infections in transplant patients
Knowledge-focused CompletedThis study followed 600 lung transplant patients to understand how common viral and bacterial infections are after transplant surgery. Researchers collected blood and lung fluid samples to see if certain infections are linked to a serious complication called bronchiolitis obliter…
Matched conditions: BRONCHIOLITIS OBLITERANS
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC