BRONCHIOLITIS OBLITERANS

This Phase 3 trial tested whether adding inhaled liposomal cyclosporine A to standard care can improve lung function in 169 double lung transplant patients with chronic rejection. Participants inhaled the drug twice daily for 48 weeks. The main goal was to see if it slowed the de…

This Phase 3 trial tested whether adding inhaled liposomal cyclosporine A to standard care helps single lung transplant patients with chronic lung rejection. 62 adults who had a single lung transplant at least a year earlier and had signs of chronic rejection took part. The study…

This study looked at whether lung MRI can diagnose bronchiolitis obliterans syndrome (BOS) after allogeneic stem cell transplant as well as chest CT scans. BOS is a serious lung complication that can occur after transplant, and early diagnosis is important. Researchers compared M…

This study followed 600 lung transplant recipients at the University of Pittsburgh to see how common viral and bacterial infections are and how they affect long-term health. Researchers focused on whether a specific infection (C. pneumoniae) is linked to a condition called bronch…

This study tested a new MRI technique using inhaled hyperpolarized xenon gas to detect early signs of bronchiolitis obliterans syndrome (BOS), a common form of chronic rejection after lung transplant. Only 3 participants were involved, and the goal was to see if the imaging could…