BRONCHIECTASIS

This study tests a daily tablet called Florensocatib (CHF10196) to see if it can reduce the number of serious lung flare-ups in people with bronchiectasis, a long-term lung condition. About 1800 participants aged 12 to 85 will take either the drug or a placebo for up to 78 weeks,…

This study tests a new medicine, GSK3862995B, for adults with bronchiectasis, a long-term lung condition that causes coughing and frequent infections. About 400 people will be randomly assigned to receive one of two doses of the drug or a placebo. The main goal is to see if the d…

This study tests a device called Simeox 200 that helps people with bronchiectasis cough up mucus more easily. About 35 adults will use the device at home for two weeks. Researchers will measure how much mucus is cleared, lung function, and quality of life to see if the device hel…

This study tests whether a Chinese herbal medicine called Lifei Qingchang Granules can help people with stable bronchiectasis breathe easier and feel better. About 150 adults aged 18-75 who have had at least one flare-up in the past year will take either the granules or a placebo…

This study tests whether a 12-week home exercise program, supervised remotely via video calls, can improve exercise ability and quality of life in adults with bronchiectasis. Eighty participants will be split into two groups: one receiving usual care and the other doing supervise…

This study looks at 300 adults with bronchiectasis, a chronic lung condition, to understand why 20-40% also suffer from anxiety or depression. Researchers will collect blood, sputum, and stool samples to analyze metabolic pathways and track mood, flare-ups, and hospital visits ov…