BREAST RECONSTRUCTION

This study is testing a material called ARTIA, used during breast reconstruction surgery after a mastectomy. The goal is to see if it is safe and works well for rebuilding the breast shape in two stages. About 264 adults who need immediate reconstruction will take part. The study…

This study looks at a new material called SC DERM® Recon, used in breast reconstruction surgery after mastectomy for breast cancer. Researchers want to see if it causes fewer short-term problems than similar materials. About 120 women will take part, and the study will track comp…

This study tests a breast reconstruction method that combines fat grafting with a muscle flap taken from the back. It is for women who have had a mastectomy and want delayed reconstruction. The goal is to see if this approach reduces wound infections and other complications.

This study tests a special absorbable mesh that releases antibiotics to help prevent infections in women undergoing two-stage breast reconstruction after mastectomy. About 702 women will be randomly assigned to receive either standard care or the new mesh. The goal is to see if t…

This study is testing a product called OviTex PRS to see if it is safe and works well for women having breast reconstruction with implants after a mastectomy (breast removal due to cancer or to prevent it). About 235 women aged 22 to 75 who are non-smokers and having their first …

This study is for women having two-stage breast reconstruction after mastectomy. It tests a special mesh (acellular dermal matrix) placed under the chest muscle to support the new breast. The goal is to see if it reduces serious complications and improves quality of life. About 4…

This study tests whether applying minoxidil (a hair growth cream) to the breasts for two weeks before surgery can improve blood flow and tissue survival in women undergoing preventive mastectomy with reconstruction. About 25 women at high genetic risk for breast cancer will parti…

This study tests if using a pulsed lavage (a high-pressure washing device) to clean the surgical pocket during implant-based breast reconstruction can lower the risk of complications like infection, bleeding, fluid buildup, or implant failure. Researchers will compare outcomes in…

This study compares two types of nipple-sparing mastectomy (keeping the nipple) for women with breast cancer or high genetic risk: one done with a robot through a single small cut, and the other with standard open surgery. All participants will also have immediate breast reconstr…

This study tests whether hyperbaric oxygen therapy (HBOT) can improve the survival of fat grafts used in breast reconstruction for women who have had radiation therapy for breast cancer. Sixteen women will each receive two fat grafting sessions, one with HBOT and one without, to …

This study compares two types of nerve blocks—paravertebral and pectoral—to see which one better reduces pain and improves physical well-being in people having immediate implant-based breast reconstruction. About 212 adults scheduled for this surgery will be enrolled. The goal is…

This study tests whether watching a short educational video about safe opioid use helps breast reconstruction patients use fewer pain pills after surgery. About 68 women having breast reconstruction after mastectomy will be randomly assigned to either watch the video or receive s…