BRCA1 MUTATION
Clinical trials for BRCA1 MUTATION explained in plain language.
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Promising drug cocktail targets BRCA breast cancer in early trial
Disease control CompletedThis early-phase study tested whether combining three drugs (olaparib, palbociclib, and fulvestrant) is safe for people with a specific type of advanced breast cancer linked to BRCA gene mutations. Nine adults with hormone receptor-positive, HER2-negative metastatic or locally ad…
Matched conditions: BRCA1 MUTATION
Phase: PHASE1 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Toolkit may help families discuss cancer gene risks
Knowledge-focused CompletedThis study looked at whether giving a 'disclosure toolkit' to people with BRCA gene mutations helps them share their genetic test results with family members who may also be at risk. Researchers enrolled 52 adults with BRCA1 or BRCA2 mutations and tracked how often they told rela…
Matched conditions: BRCA1 MUTATION
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:13 UTC