BRAIN DISEASES
Clinical trials for BRAIN DISEASES explained in plain language.
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New dosing strategy aims to make Alzheimer's drug safer and more effective
Disease control OngoingThis study tests different dosing schedules of the drug donanemab in about 1,175 people with early symptomatic Alzheimer's disease. The goal is to find a regimen that lowers brain amyloid plaques while reducing the risk of a side effect called ARIA-E (brain swelling or small blee…
Matched conditions: BRAIN DISEASES
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a new drug slow Alzheimer's? large trial underway
Disease control OngoingThis phase 3 study tests whether donanemab, an antibody given through an IV, can safely slow cognitive decline in 1500 people with early Alzheimer's. Participants receive either the drug or a placebo for up to 93 weeks. The main goal is to measure changes in thinking and daily fu…
Matched conditions: BRAIN DISEASES
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Brain tissue collection aims to fuel future discoveries
Knowledge-focused ENROLLING_BY_INVITATIONThis study collects brain tissue samples from up to 2,500 adults and children undergoing brain surgery. The samples are stored in a tissue bank for use in future approved research projects. The goal is to provide a valuable resource for scientists studying brain diseases.
Matched conditions: BRAIN DISEASES
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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300 volunteers help create medical image bank for science
Knowledge-focused OngoingThis study gathers MRI, CT, and ultrasound images from 300 adults—some healthy, some with kidney or brain disease—to build a collection for future not-for-profit research. No new treatments are being tested; the goal is to make medical images available to scientists for advancing…
Matched conditions: BRAIN DISEASES
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:28 UTC