BIPOLAR 1 DISORDER

This study is testing whether an investigational drug called RAP-219 can safely and effectively treat acute manic episodes in people with bipolar I disorder. 224 adult participants experiencing a manic episode will receive either RAP-219 or a placebo during a 3-week inpatient sta…

This study aims to see if a specific brain activity pattern, called Biotype-1, can predict which people with schizophrenia, schizoaffective disorder, or bipolar disorder with psychosis will respond exceptionally well to the medication clozapine. About 320 participants will be ran…

This study is testing a new monthly injection of a medication called cariprazine for people with schizophrenia, bipolar disorder, or major depression. It aims to see if the injection is safe, how the body processes it, and if it helps control symptoms. The study will enroll 24 ad…

This study is testing whether wearing glasses that block blue light is a practical and helpful tool for people hospitalized with a manic episode of bipolar disorder. Researchers will enroll 25 adults to see if they can wear the glasses for a week and if doing so might help reduce…

This study aims to understand the early stages of psychotic disorders like schizophrenia and bipolar disorder. Researchers will collect information from 320 people recently diagnosed, including brain scans, eye movement tests, and genetic samples, to see if these biological marke…