BACK PAIN LOWER BACK CHRONIC
Clinical trials for BACK PAIN LOWER BACK CHRONIC explained in plain language.
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Sleep hormone melatonin tested as painkiller for chronic back pain
Symptom relief CompletedThis study tested whether taking melatonin before bed can reduce pain and improve sleep in people with chronic low back pain and insomnia. About 220 adults aged 18 to 64 with back pain for at least 3 months and sleep problems took either melatonin or a placebo for several weeks. …
Matched conditions: BACK PAIN LOWER BACK CHRONIC
Phase: PHASE3 • Sponsor: Odense University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Magnesium may ease pain after back surgery, small study suggests
Symptom relief CompletedThis study looked at whether giving a low dose of magnesium sulfate during lower back surgery can help reduce pain afterward. Sixty adults having lumbar spine surgery received either magnesium or a placebo. The goal was to see if magnesium could lower pain scores and the need for…
Matched conditions: BACK PAIN LOWER BACK CHRONIC
Phase: NA • Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Spine steroid shot eases back pain for a month, but not a year
Symptom relief CompletedThis study tested whether a steroid injection directly into the spinal disc could reduce pain in people with chronic lower back pain and disc inflammation (Modic I). 137 participants received either the steroid or a placebo. The steroid helped lower pain at 1 month, but the effec…
Matched conditions: BACK PAIN LOWER BACK CHRONIC
Phase: PHASE4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 26, 2026 16:28 UTC
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Brain scans reveal hidden inflammation in chronic back pain sufferers
Knowledge-focused CompletedThis study used special brain scans to look for signs of inflammation in the brains and spinal cords of 60 people with chronic low back pain. Researchers also tested whether a short course of the antibiotic minocycline could reduce both inflammation and pain. The goal was to bett…
Matched conditions: BACK PAIN LOWER BACK CHRONIC
Phase: PHASE2 • Sponsor: Marco Loggia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC