ATRIAL SEPTAL DEFECT
Clinical trials for ATRIAL SEPTAL DEFECT explained in plain language.
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Which breathing setting keeps Kids' lungs healthier during heart surgery?
Disease control CompletedThis trial asks whether one way of setting a breathing machine is better than another for children born with a hole in the heart who are having surgery to close it. The hole lets extra blood flow to the lungs, which can make them stiff and harder to inflate. During surgery, a mac…
Matched conditions: ATRIAL SEPTAL DEFECT
Phase: NA • Sponsor: Nilratan Sircar Medical College • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Vitamin B1 shows promise for Kids' hearts after hole closure
Disease control CompletedThis study looked at whether giving thiamine (vitamin B1) for 28 days after a heart defect repair procedure helps children's hearts recover. The trial included 86 children aged 6 months to 18 years with certain heart defects. Researchers measured heart structure and function usin…
Matched conditions: ATRIAL SEPTAL DEFECT
Phase: EARLY_PHASE1 • Sponsor: Universitas Sumatera Utara • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New device plugs heart holes without open surgery
Disease control CompletedThis study tested a special device (GORE® CARDIOFORM ASD Occluder) to close a common type of hole in the heart called an atrial septal defect (ASD). The goal was to see if the device could safely and effectively seal the hole using a tube inserted through a blood vessel, avoiding…
Matched conditions: ATRIAL SEPTAL DEFECT
Phase: NA • Sponsor: W.L.Gore & Associates • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Dissolvable heart patch offers hope for kids with hole in the heart
Disease control CompletedThis study tested a new device called Absnow that can close a common type of hole in the heart (atrial septal defect) and then dissolve over time. 165 patients, including children as young as 3, received the device. The goal was to see if it safely closes the hole without major p…
Matched conditions: ATRIAL SEPTAL DEFECT
Phase: NA • Sponsor: Lifetech Scientific (Shenzhen) Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New study aims to spot heart defects in newborns with simple blood test
Diagnosis CompletedThis completed study looked at 313 children to see if blood tests and advanced heart scans could help detect congenital heart disease earlier and predict which children might need surgery. Researchers compared children with heart defects to healthy controls using blood biomarkers…
Matched conditions: ATRIAL SEPTAL DEFECT
Phase: NA • Sponsor: Lund University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:30 UTC
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New study: sedation may be as safe as general anesthesia for Kids' heart procedure
Symptom relief CompletedThis study looked at 60 children aged 3-8 years who needed a procedure to close a hole in their heart. Researchers compared general anesthesia to a lighter sedation combined with numbing medicine at the catheter site. They measured heart rate and blood pressure to see which appro…
Matched conditions: ATRIAL SEPTAL DEFECT
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Cartoon therapy cuts pain in young heart patients
Symptom relief CompletedThis study tested if combining cartoon-watching with nurse interaction could ease pain in children after heart surgery. 70 kids aged 3-7 took part; half got standard pain care, and the other half also watched cartoons with a nurse. The goal was to see if this fun, non-drug approa…
Matched conditions: ATRIAL SEPTAL DEFECT
Phase: NA • Sponsor: Beijing Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Can a Stick-On AI patch replace wires for heart monitoring after surgery?
Knowledge-focused CompletedThis study tests a small, wearable ECG patch that uses artificial intelligence to monitor heart rhythms in patients recovering from cardiac surgery. Participants wear the patch for up to a week after leaving the intensive care unit. The goal is to see if the device can reliably t…
Matched conditions: ATRIAL SEPTAL DEFECT
Phase: NA • Sponsor: HUINNO Co., Ltd • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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New heart imaging device tested in small study
Knowledge-focused CompletedThis study tested a new imaging system called VERAFEYE in 18 people already scheduled for standard heart procedures like ablation or closure. Doctors used the device during the procedure and gave feedback via a questionnaire. The goal was to gather information to improve the syst…
Matched conditions: ATRIAL SEPTAL DEFECT
Phase: NA • Sponsor: LUMA Vision Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC