AORTIC VALVE CALCIFICATION
Clinical trials for AORTIC VALVE CALCIFICATION explained in plain language.
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New heart valve device tested in humans for first time
Disease control OngoingThis study tests a new device called the DurAVR™ THV System, a replacement heart valve placed through a small tube in an artery, for people with severe aortic stenosis (a narrowed heart valve). The trial involves 150 participants and aims to see if the device is safe and works we…
Matched conditions: AORTIC VALVE CALCIFICATION
Phase: NA • Sponsor: Anteris Technologies Ltd. • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New heart valve shows promise in early trial for aortic stenosis
Disease control OngoingThis early study tests a new device called the DurAVR™ heart valve in 15 people aged 65 and older with severe aortic stenosis, a condition where the heart's aortic valve becomes narrowed. The valve is implanted through a catheter (TAVR) without open-heart surgery. The main goals …
Matched conditions: AORTIC VALVE CALCIFICATION
Phase: NA • Sponsor: Anteris Technologies Ltd. • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New heart valve device shows early promise in small study
Disease control OngoingThis early study is testing a new device called the DurAVR™ THV System, which is a replacement heart valve placed through a small tube in the leg (TAVI procedure). The study includes 40 people with severe aortic stenosis or a failed surgical valve. The main goal is to see if the …
Matched conditions: AORTIC VALVE CALCIFICATION
Phase: NA • Sponsor: Anteris Technologies Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Could a common gout drug save hearts? colchicine trial targets valve disease
Disease control OngoingThis phase 3 trial tests whether colchicine, an anti-inflammatory drug, can slow the progression of aortic valve stenosis—a narrowing of the heart's aortic valve that currently has no drug treatment. The study enrolls 150 people with moderate, symptom-free valve disease. Particip…
Matched conditions: AORTIC VALVE CALCIFICATION
Phase: PHASE3 • Sponsor: Radboud University Medical Center • Aim: Disease control
Last updated Jun 26, 2026 16:46 UTC
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Heart valve mystery: scientists hunt for genetic clues in 1,000 patients
Knowledge-focused OngoingThis study collects tissue samples from 1,000 people having heart valve surgery to find genetic causes of calcific aortic valve disease. Researchers will compare normal and diseased tissue to understand why the disease develops. Participants must be at least 20 years old and have…
Matched conditions: AORTIC VALVE CALCIFICATION
Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC