ANHEDONIA

This study tests a new non-invasive brain stimulation tool called kTMP to treat anhedonia, the loss of interest or pleasure, in people with major depressive disorder. 104 participants will receive either active or sham stimulation. The main goal is to see if kTMP changes brain ac…

This early-stage study tests whether a single 25 mg dose of psilocybin can help people who still feel emotionally flat or uninterested in things despite taking antidepressants. About 90 adults aged 18-65 will receive either psilocybin or a placebo, and researchers will use brain …

This study tests a group training program called Positive Events Training (PET) for adolescents aged 12-16 who have mild to moderate depressive symptoms. The program teaches teens to recall and imagine positive events more vividly, aiming to increase daily positive emotions and r…

This study uses a virtual reality task to measure how people with depression make decisions involving physical effort and reward. Participants will walk on a treadmill in a VR environment while researchers track brain activity, heart rate, and energy use. The goal is to better un…

This study will test an enhanced version of a suicide safety planning app called ViraSafe in 100 teens and young adults (ages 13-24) who have recently attempted suicide or had serious suicidal thoughts. The goal is to see if the app helps them engage more with coping skills and t…