ANEURYSMAL SUBARACHNOID HEMORRHAGE

This study tests whether the steroid fludrocortisone can help people recover better after a serious type of stroke called aneurysmal subarachnoid hemorrhage (aSAH). About 524 adults in intensive care will receive either the drug or a placebo. The goal is to see if early treatment…

This study looks at whether injecting the drug nicardipine directly into the fluid around the brain and spine can help people who have dangerous artery spasms after a bleeding stroke. About 396 adults who already have a drain in place will be randomly assigned to get the drug or …

This study is testing a device called NeVa VS that helps open narrowed brain arteries in people who have had a certain type of stroke (aneurysmal subarachnoid hemorrhage). The device is already approved for emergency use. Researchers will watch 200 adults to see how well the devi…

This study tests whether placing a drain in the lower back and injecting a clot-busting drug (urokinase) soon after a severe brain bleed improves recovery. About 424 adults with a first-time severe aneurysm bleed will receive either the active treatment or a placebo, along with s…

This study tests a drug called deferoxamine in people who have had a severe type of stroke caused by a burst brain aneurysm. The drug works by removing extra iron that can damage the brain after the bleeding. Researchers want to see if it helps patients recover better over six mo…

This study tests a drug called tocilizumab-aazg in 30 adults who have had a burst brain aneurysm. The goal is to see if the drug is safe and might help prevent strokes that can happen after the bleeding. Participants will receive the drug within 24 hours of the aneurysm rupture a…

This study tests whether a numbing nasal spray can safely reduce severe headaches after a brain aneurysm bleed. About 20 adults in the ICU will receive the spray along with standard pain meds. Researchers will compare pain levels and opioid use before and after treatment to see i…

This study looks at whether levels of nitric oxide in spinal fluid can predict dangerous blood vessel spasms after a type of brain bleed called subarachnoid hemorrhage. Researchers will compare nitric oxide levels in 40 patients with and without this condition. The goal is to fin…

This study follows 8,000 adults who have had a stroke to learn why some develop memory and thinking problems afterward. Researchers will track changes in cognition, brain scans, and blood samples over time. The goal is to help doctors identify who is at risk for dementia and pave…

This study aims to understand why some people have worse outcomes after a brain bleed (aneurysmal subarachnoid hemorrhage). Researchers will collect blood, spinal fluid, urine, and other samples from 2000 patients across multiple hospitals. By analyzing genes, proteins, and other…

This study looks at a new way to treat severe brain bleeds caused by a burst aneurysm. Instead of coiling the whole aneurysm, doctors will only coil the dome (the bulging part). The goal is to see if this lowers the chance of re-bleeding. The study will enroll 30 adults with seve…

This study is tracking 5,000 people who had a brain bleed from a ruptured aneurysm. Researchers want to find out which factors lead to complications, disability, or death. By collecting data from many hospitals, they hope to build better tools to predict recovery and improve care…

This study is collecting information from 1,000 people who have been treated for brain aneurysms or stroke using MicroVention devices. The goal is to see how well these treatments work in real life, not just in controlled trials. Researchers will track how completely aneurysms ar…