Spinal injection may prevent brain damage after aneurysm
NCT ID NCT06329635
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether injecting the drug nicardipine into the spinal fluid can improve recovery in people who develop blood vessel spasms after a brain aneurysm bleed. About 396 adults aged 18–80 will receive either the drug or a sham procedure. The goal is to see if the treatment reduces long-term disability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nicardipine
What this could lead to
If it works, this could provide a new way to treat dangerous blood vessel spasms after a brain aneurysm bleed, potentially reducing disability.
What could go wrong
This is a mid-stage trial with 396 participants, so results are not yet proven. The treatment involves a spinal injection, which carries risks like infection or bleeding.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Affiliated First Hospital of Anhui Medical University
RECRUITINGHefei, Anhui, 230000, China
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Affiliated South China Hospital of Shenzhen University
RECRUITINGShenzhen, Guangdong, 518111, China
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Baotou Central Hospital
RECRUITINGBaotou, Inner Mongolia, 014040, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beijing Tiantan Hospital, Affiliated to Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100070, China
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Changzhou First People's Hospital
RECRUITINGChangzhou, Jiangsu, 213004, China
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Chongqing Ninth People's Hospital
RECRUITINGChongqing, Chongqing Municipality, 400799, China
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Ganzhou People's Hospital
RECRUITINGGanzhou, Jiangxi, 341000, China
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Jinggangshan University Affiliated Hospital
RECRUITINGJi’an, Jiangxi, 343099, China
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Jinyang Hospital Affiliated to Guizhou Medical University
RECRUITINGGuiyang, Guizhou, 550080, China
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Liupanshui City People's Hospital
RECRUITINGLiupanshui, Guizhou, 553400, China
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Nanning First People's Hospital
RECRUITINGNanning, Guangxi, 530016, China
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Nanyang Central Hospital, Henan Province
RECRUITINGNanyang, Henan, 473005, China
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People's Hospital of Qiannan Buyi and Miao Autonomous Prefecture, Guizhou Province
RECRUITINGXingyi, Guizhou, 558000, China
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Qianfengdong Prefecture People's Hospital
RECRUITINGKaili, G, 556099, China
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Qianxinan Prefecture People's Hospital
RECRUITINGXingyi, Guizhou, 562499, China
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Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, 201112, China
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Southern Medical University Zhujiang Hospital
RECRUITINGGuangzhou, Guangdong, 510260, China
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Taian Central Hospital, Shandong Province
RECRUITINGTai’an, Shandong, 27109, China
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The First Affiliated Hospital of Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310000, China
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The First Hospital of Shanxi Medical University
RECRUITINGTaiyuan, Shanxi, 030001, China
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The First People's Hospital of Zhenjiang City, Jiangsu Province
RECRUITINGZhenjiang, Jiangsu, 212002, China
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The Second Affiliated Hospital of Guizhou Medical University
RECRUITINGKaili, Guizhou, 556099, China
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The Second Affiliated Hospital of Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310009, China
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The Second Hospital of Hebei Medical University
RECRUITINGShijiazhuang, Hebei, 230601, China
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West China Airport Hospital of Sichuan University
RECRUITINGChengdu, Sichuan, 610299, China
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Western Medical University Affiliated Hospital
RECRUITINGLuzhou, Sichuan, 646099, China
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Xingyi City People's Hospital
RECRUITINGXingyi, Guizhou, 562499, China
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Zhejiang Hospital
RECRUITINGHangzhou, Zhejiang, 310007, China
Contact