Spinal injection may prevent brain damage after aneurysm rupture
NCT ID NCT06329635
First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 25 times
Summary
This study tests whether injecting the blood pressure drug nicardipine directly into the spinal fluid can improve recovery in people who develop dangerous blood vessel spasms after a brain aneurysm rupture. About 396 adults aged 18-80 who have had a brain aneurysm treated and a drain placed in their head or spine will be randomly assigned to receive either nicardipine or a placebo through that drain. The main goal is to see if more patients achieve a good level of daily function three months later.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Affiliated First Hospital of Anhui Medical University
RECRUITINGHefei, Anhui, 230000, China
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Affiliated South China Hospital of Shenzhen University
RECRUITINGShenzhen, Guangdong, 518111, China
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Baotou Central Hospital
RECRUITINGBaotou, Inner Mongolia, 014040, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beijing Tiantan Hospital, Affiliated to Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100070, China
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Changzhou First People's Hospital
RECRUITINGChangzhou, Jiangsu, 213004, China
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Chongqing Ninth People's Hospital
RECRUITINGChongqing, Chongqing Municipality, 400799, China
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Ganzhou People's Hospital
RECRUITINGGanzhou, Jiangxi, 341000, China
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Jinggangshan University Affiliated Hospital
RECRUITINGJi’an, Jiangxi, 343099, China
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Jinyang Hospital Affiliated to Guizhou Medical University
RECRUITINGGuiyang, Guizhou, 550080, China
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Liupanshui City People's Hospital
RECRUITINGLiupanshui, Guizhou, 553400, China
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Nanning First People's Hospital
RECRUITINGNanning, Guangxi, 530016, China
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Nanyang Central Hospital, Henan Province
RECRUITINGNanyang, Henan, 473005, China
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People's Hospital of Qiannan Buyi and Miao Autonomous Prefecture, Guizhou Province
RECRUITINGXingyi, Guizhou, 558000, China
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Qianfengdong Prefecture People's Hospital
RECRUITINGKaili, G, 556099, China
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Qianxinan Prefecture People's Hospital
RECRUITINGXingyi, Guizhou, 562499, China
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Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, 201112, China
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Southern Medical University Zhujiang Hospital
RECRUITINGGuangzhou, Guangdong, 510260, China
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Taian Central Hospital, Shandong Province
RECRUITINGTai’an, Shandong, 27109, China
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The First Affiliated Hospital of Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310000, China
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The First Hospital of Shanxi Medical University
RECRUITINGTaiyuan, Shanxi, 030001, China
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The First People's Hospital of Zhenjiang City, Jiangsu Province
RECRUITINGZhenjiang, Jiangsu, 212002, China
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The Second Affiliated Hospital of Guizhou Medical University
RECRUITINGKaili, Guizhou, 556099, China
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The Second Affiliated Hospital of Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310009, China
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The Second Hospital of Hebei Medical University
RECRUITINGShijiazhuang, Hebei, 230601, China
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West China Airport Hospital of Sichuan University
RECRUITINGChengdu, Sichuan, 610299, China
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Western Medical University Affiliated Hospital
RECRUITINGLuzhou, Sichuan, 646099, China
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Xingyi City People's Hospital
RECRUITINGXingyi, Guizhou, 562499, China
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Zhejiang Hospital
RECRUITINGHangzhou, Zhejiang, 310007, China
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Conditions
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