AMYLOIDOSIS

This study tested whether adding daratumumab to standard chemotherapy (CyBorD) helps people newly diagnosed with AL amyloidosis, a rare disease where abnormal proteins build up in organs. About 416 adults took part. The goal was to see if the combination leads to better blood res…

This study tested whether a special PET/MR scan using a tracer called F-18 florbetapir can detect amyloid deposits in the nerves of people with amyloidosis. Eight adults with confirmed nerve amyloidosis or other nerve diseases were scanned. The goal was to see if the scan could t…

This study tested a new radioactive tracer called 124I AT-01 to see how well it can measure amyloid buildup in organs using PET/CT scans. 33 adults with systemic amyloidosis (AL or ATTR type) received the tracer and were scanned twice to check if the results were consistent. The …

This study followed 37 people who carry a genetic mutation for hereditary ATTR amyloidosis but do not yet have symptoms. Over five years, researchers measured a specific misfolded protein in the blood to see if it changes when the disease starts or when treatment is given. The go…

This study looked at 721 Russian patients with carpal tunnel syndrome to see how many also had a rare inherited nerve disease called hereditary transthyretin amyloidosis. Researchers reviewed medical records and did genetic testing. The goal was to understand how common this cond…

This study looked at 51 adults with cardiac amyloidosis, a rare heart condition, to find out how many also have problems with smell and taste. Researchers used simple tests to measure these senses. The goal was to see if smell or taste loss could help doctors catch the disease ea…