ALCOHOLISM
Clinical trials for ALCOHOLISM explained in plain language.
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Longer detox may curb alcohol relapse
Disease control CompletedThis study looked at whether giving a longer course of diazepam (one month instead of the usual one week) during alcohol detox could help prevent people from drinking again soon after. 26 adults with alcohol dependence took part. The goal was to see if the longer treatment reduce…
Matched conditions: ALCOHOLISM
Phase: NA • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 12, 2026 12:03 UTC
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New combo therapy for alcoholism shows early promise in small study
Disease control CompletedThis pilot study tested whether adding N-Acetyl Cysteine (NAC) to the medication Topiramate is safe and tolerable for people with alcohol use disorder. Seventeen adults who drank heavily and wanted treatment took either Topiramate plus NAC or Topiramate plus a placebo. The main g…
Matched conditions: ALCOHOLISM
Phase: EARLY_PHASE1 • Sponsor: Nassima Ait-Daoud Tiouririne • Aim: Disease control
Last updated Jun 11, 2026 12:09 UTC
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Can a muscle relaxant curb alcohol cravings? new trial investigates
Disease control CompletedThis study tested whether the drug baclofen helps people with alcoholism reduce their drinking to safe levels or stop completely over one year. 323 adults who wanted to cut back or quit alcohol took either baclofen or a placebo pill. The goal was to see if more people on baclofen…
Matched conditions: ALCOHOLISM
Phase: PHASE2, PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 08, 2026 13:10 UTC
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Brain zaps may boost thinking in alcohol recovery
Symptom relief CompletedThis small pilot study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) could improve cognitive flexibility in people recently detoxified from alcohol. Fourteen adults with alcohol use disorder received either re…
Matched conditions: ALCOHOLISM
Phase: NA • Sponsor: Nassima Ait-Daoud Tiouririne • Aim: Symptom relief
Last updated Jun 15, 2026 19:07 UTC
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ADHD may raise relapse risk in alcohol recovery
Knowledge-focused CompletedThis study looked at whether adults with attention deficit hyperactivity disorder (ADHD) are more likely to relapse into drinking after completing a detox program. Researchers followed 113 people for 12 weeks after detox, using both a screening questionnaire and a more thorough d…
Matched conditions: ALCOHOLISM
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC
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Can better sleep prevent alcohol relapse? new study investigates
Knowledge-focused CompletedThis study looked at how sleep problems might lead to relapse in people recovering from alcohol dependence. Researchers followed 198 adults leaving inpatient treatment, using sleep questionnaires and activity monitors to track sleep quality. The goal was to understand if poor sle…
Matched conditions: ALCOHOLISM
Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:03 UTC
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Can a smartphone app help prevent suicide? new study investigates
Knowledge-focused CompletedThis study tested a mobile app called WisePath designed to help adults who are thinking about suicide and may also misuse alcohol. Over 12 weeks, 127 participants either used the WisePath app or received standard self-help resources. Researchers measured changes in suicidal thoug…
Matched conditions: ALCOHOLISM
Phase: NA • Sponsor: Evidence-Based Practice Institute, Seattle, WA • Aim: Knowledge-focused
Last updated Jun 11, 2026 12:10 UTC
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Gut bugs linked to alcohol cravings in new study
Knowledge-focused CompletedThis study looked at how gut bacteria differ between people with alcohol use disorder who are currently drinking, those who are abstinent, and healthy moderate drinkers. Researchers collected stool samples and measured cravings in a bar-like setting. The goal was to understand if…
Matched conditions: ALCOHOLISM
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Jun 11, 2026 11:57 UTC