New combo therapy for alcoholism shows early promise in small study
NCT ID NCT03120468
First seen Jun 10, 2026 · Last updated Jun 10, 2026
Summary
This pilot study tested whether adding N-Acetyl Cysteine (NAC) to the medication Topiramate is safe and tolerable for people with alcohol use disorder. Seventeen adults who drank heavily and wanted treatment took either Topiramate plus NAC or Topiramate plus a placebo. The main goal was to check for side effects like trouble thinking, not to measure how well the treatment worked.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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UVA Center for Leading Edge Addiction Research
Charlottesville, Virginia, 22903, United States
Conditions
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Conditions inferred from the trial description
These were inferred from the trial's summary, not listed by the trial registrant.