ALCOHOL USE

This early-stage study tests whether the psychedelic DMT, combined with talk therapy, can help people with alcohol use disorder drink less. About 63 adults with the condition will receive either DMT or a placebo in a controlled setting. Researchers will monitor safety and measure…

This study tests whether guanfacine, a blood pressure medication, can reduce alcohol consumption in people with alcohol use disorder. Researchers will see how the drug affects drinking after stress or stimulation, and whether it works differently in men versus women. About 160 ad…

This study looks at whether mindfulness-based relapse prevention, combined with wearable heart rate sensors, can help people with alcohol use disorder drink less and feel better. About 120 adults will attend weekly group sessions for 8 weeks, answer questions about mood and drink…

This study tests a short, tailored alcohol intervention for 60 adults who are taking buprenorphine for opioid use and also drink alcohol. The program aims to reduce drinking and improve treatment satisfaction. Researchers will check if the approach is practical and liked by parti…

This study tests a short program to help young adults (ages 18-29) who have trouble sleeping and also drink heavily or use marijuana. The goal is to see if the program can reduce drinking and cannabis use while improving sleep. About 800 people in Washington State will take part.

This study looks at how alcohol use, suicidal thoughts, and decision-making are related in adults who drink regularly. About 100 participants will try a self-guided online program based on cognitive behavioral therapy and complete surveys over three months. The goal is to underst…

This study is testing a program called Get Better Together for military couples. The goal is to see if attending a weekend retreat helps couples handle stress, improves mental health, and reduces problems like drinking too much, fighting, or thoughts of suicide. About 1000 couple…

This study looks at whether setting personal goals can help college students use protective strategies—like pacing drinks or eating before drinking—to reduce alcohol-related harm. Researchers will compare three groups: one that gets basic information, one that picks strategies to…

This study looks at how much parents should be involved when teens get brief counseling for mild alcohol problems during regular doctor visits. Researchers will compare no parent involvement, a live session with a parent, or an online program for parents. The goal is to find the …