Psychedelic DMT trial aims to curb alcohol addiction

NCT ID NCT06070649

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study tests whether the psychedelic drug DMT, combined with psychotherapy, can help people with alcohol use disorder. 63 participants will receive either a moderate or low dose of DMT, or a placebo, and their safety and desire to drink will be measured. The goal is to see if the psychedelic experience can reduce alcohol consumption.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DMT (dimethyltryptamine), a psychedelic drug

What this could lead to

If it works, this could point toward a new treatment option for alcohol use disorder that combines a psychedelic experience with therapy.

What could go wrong

This is a very early Phase 1 trial with only 63 people, focused on safety. It is too soon to know if DMT actually helps reduce drinking, and psychedelics can cause intense psychological reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcohol abuse Alcohol Drinking alcohol-related disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Connecticut Mental Health Center

    RECRUITING

    New Haven, Connecticut, 06519, United States

    Contact Email: •••••@•••••

    Contact