ALCOHOL DEPENDENCE
Clinical trials for ALCOHOL DEPENDENCE explained in plain language.
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Brain zaps may curb alcohol cravings, study finds
Disease control CompletedThis study tested a non-invasive brain stimulation technique called TMS to see if it could help people with alcohol use disorder drink less. 147 adults who wanted to cut back on drinking received TMS and were tracked for 4 months. The goal was to measure changes in drinking days,…
Matched conditions: ALCOHOL DEPENDENCE
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Longer diazepam use may curb alcohol relapse
Disease control CompletedThis study tested whether giving people with alcohol dependence a one-month course of diazepam (40 mg per day) after detoxification could reduce the chance of relapsing into drinking within the next three months. The standard detoxification treatment is usually about one week. Th…
Matched conditions: ALCOHOL DEPENDENCE
Phase: NA • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Can a seizure drug help you quit drinking and smoking?
Disease control CompletedThis study tested whether topiramate, a seizure medication, can help people who are dependent on both alcohol and nicotine. 236 adults received either a low or high dose of topiramate or a placebo, plus behavioral therapy. The goal was to see if the drug could reduce heavy drinki…
Matched conditions: ALCOHOL DEPENDENCE
Phase: PHASE2, PHASE3 • Sponsor: University of Virginia • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Phone app and debit card help fight alcohol addiction in new study
Disease control CompletedThis study tested a smartphone-based program that uses rewards, coaching, and breathalyzer tests to help 236 adults with alcohol use disorder reduce drinking. Participants earned money for staying sober, tracked via breath tests and self-reports. The goal was to see if this digit…
Matched conditions: ALCOHOL DEPENDENCE
Phase: NA • Sponsor: DynamiCare Health • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Can a phone app keep you sober? new study tests Anti-Alcohol training
Prevention CompletedThis study tested a smartphone app designed to help people recovering from alcohol dependence avoid relapse. The app uses a training game to change unconscious habits that make people reach for alcohol. 600 participants used either the active training or a placebo version. The go…
Matched conditions: ALCOHOL DEPENDENCE
Phase: NA • Sponsor: Salus Klinik Lindow • Aim: Prevention
Last updated Jun 27, 2026 12:26 UTC
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Gut bacteria may hold key to alcohol addiction treatment
Knowledge-focused CompletedThis study looked at 23 adults going through alcohol detox to see how the bacteria in their mouth and gut change over time. Researchers collected stool and mouth samples along with diet and mood questionnaires. The goal was to better understand the link between gut bacteria, anxi…
Matched conditions: ALCOHOL DEPENDENCE
Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Sleep problems may predict alcohol relapse after rehab
Knowledge-focused CompletedThis study looked at how sleep quality and beliefs about sleep affect the risk of relapse in people recovering from alcohol dependence. Researchers followed 198 adults as they left inpatient rehab and returned home, measuring sleep with questionnaires and activity monitors. The g…
Matched conditions: ALCOHOL DEPENDENCE
Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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A quick sleep check could help prevent relapse in alcohol recovery
Knowledge-focused CompletedSleep problems affect up to 90% of people with alcohol dependence and often lead to relapse. This study tests whether a short questionnaire called the Short Sleep Index (SSI) can reliably measure sleep quality compared to a longer, standard sleep questionnaire. Researchers will a…
Matched conditions: ALCOHOL DEPENDENCE
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists use brain scans and phones to decode addiction
Knowledge-focused CompletedThis study combined brain imaging with real-world data from mobile devices to explore how addiction affects the brain. Researchers scanned the brains of 107 people with alcohol, cannabis, or nicotine dependence, along with healthy controls. They also tracked cravings and daily fu…
Matched conditions: ALCOHOL DEPENDENCE
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Study reveals how alcohol addiction and childhood stress rewire fear responses
Knowledge-focused CompletedThis study looked at whether people with alcohol dependence or a history of early life stress have more trouble learning to feel calm after a scary event. Researchers used brain scans, mild electric shocks, and genetic tests to understand these differences. The goal was to learn …
Matched conditions: ALCOHOL DEPENDENCE
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Can virtual reality help fight alcohol addiction?
Knowledge-focused CompletedThis study looked at whether a strong sense of 'presence' during virtual reality therapy could help people with alcohol dependence manage cravings and avoid relapse. Sixty abstinent patients who had recently completed withdrawal treatment took part. Researchers measured craving l…
Matched conditions: ALCOHOL DEPENDENCE
Sponsor: Charite University, Berlin, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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ADHD may raise alcohol relapse risk, study finds
Knowledge-focused CompletedThis study looked at whether adults with ADHD are more likely to relapse into drinking after completing a detox program. Researchers followed 113 people for 12 weeks, using interviews and questionnaires to assess ADHD and other mental health conditions. The goal was to see if ADH…
Matched conditions: ALCOHOL DEPENDENCE
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC